In the cells these new studies antitumor activity to show in extra-hepatic tumors, highlighting the potential for effective delivery of siRNAs to sites outside the liver. Confirm these new results and the anti-angiogenic effect of ALN – VSP and provides additional our our dual – targeting strategy. ‘.. – labeled anti – angiogenic effects of ALN – VSP treatment, including reductions in both tumor vascular density and intratumoral bleeding and – similar anti-angiogenic results with an LNP, the only the VEGF siRNA, demonstrating that the vascular effects of VEGF are silencing. – ‘We are very pleased with these new results encouraging because they anti-tumor activity of ALN – VSP in primary and metastatic disease settings to show,’said David Bumcrot, Director of Research at Alnylam.
‘The RNAi therapeutic targets two well-validated genes critical for tumor cell proliferation and survival, support an attractive strategy through the current data for the further development of novel anti-cancer drugs. Meanwhile, we continue to make progress in our Phase I with with ALN – VSP having now enrolled forward a substantial part of the study several dose groups and forward to the preliminary results in mid-2010. ‘.. The liver.resents New Pre-clinical Data on ALN – VSP, an RNAi therapeutic for the treatment of liver cancerAlnylam Pharmaceuticals , a leading RNAi therapeutics, announced new preclinical data from ALN – VSP program at the AACR-NCI-EORTC Molecular presented targets and cancer Therapeutics International Conference, November – 19, 2009 in Boston, Massachusetts is ALN – VSP an RNAi therapeutics currently in a phase I clinical trial for the treatment of liver cancers, including hepatocellular carcinoma and other solid tumors with liver involvement.Additional results of in the current survey be the following: – Forty-two health information exchange efforts of are now in the advanced stage of development and fully working, a 31 percent increase by the 32 operational initiatives in 2007. In previous years, Health Information Exchanges concentrate their focus its efforts on supporting direct maintenance supply. 2008 Result the poll show that 26 of the 42 operational initiatives provide clinical messaging, Results The delivery, or clinical documentation for be one of its services. Provide warnings either sixteen providers, advice / agency services or registration or eligible review.